253 of 2048« Return to Image BankGeneral Image Bank
"CRISPR Molecule Splits DNA"Image by Veronica Falconieri Hays (visit gallery »)
Copyright © 2017 Veronica Falconieri Hays. This image is available for reuse purchase.
Please review the Comp. Usage Agreement before downloading this image.
TitleCRISPR Molecule Splits DNA Contact
»Veronica Falconieri Hays DescriptionCover image accompanying article on CRISPR complex (Csy) from bacteria in complex with DNA and inhibitors. The molecule binds to invading bacteriophage (virus) DNA (orange) and splits the double helix open, preparing it for degradation by Cas proteins. Bacteria that deploy this immune system successfully can fend off viral invaders. Guo et al. Cryo-EM structures reveal mechanism and inhibition of DNA targeting by a CRISPR-Cas surveillance complex. Cell. 2017 Oct 5;171(2):414-426.e12. KeywordsCRISPR, bacteria, bacterium, phage, bacteriophage, virus, DNA, template, RNA, cryoEM, cryo-electron microscopy, journal cover, cover, CRISPR-Cas, inhibitor, 3D, PDB, molecular, structural biology Media Color Categories Medical, Science Subject(s) Histology, Microbial, Microscopic, Molecular, Pharmaceutical, Editorial Medical Illustration